
Matlacha Isles Holidays
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Where to stay in Matlacha Isles
Find the best Matlacha Isles areas and neighborhoods for the activities you enjoy most. Learn more about Matlacha Isles

Pelican
1 out of top 10 points of interest in this area
4/5(1 area review)
While visiting Pelican, you might make a stop by sights like Tarpon Point and Harbour View Gallery.
Top hotels in Matlacha Isles

Lani Kai Beachfront Resort
1400 Estero Blvd, Fort Myers Beach, FL
Fully refundableReserve now, pay when you stay
The price is €218 per night from 16 Jul to 17 Jul
€218
per night
16 Jul - 17 Jul
8.4/10 Very Good! (1,030 reviews)
"Close to everything you would need , great dining , my family had a great time during our stay , the staff was very friendly, and all the amenities you would need .. I would go back for a longer stay, 👍"
Reviewed on 10 Jul 2025

Sanibel Island Beach Resort
1231 Middle Gulf Dr, Sanibel, FL
Fully refundableReserve now, pay when you stay
The price is €239 per night from 10 Aug to 11 Aug
€239
per night
10 Aug - 11 Aug
8.8/10 Excellent! (1,195 reviews)
"So close to beach awesome time."
Reviewed on 9 Jul 2025

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
1538 Cape Coral Pkwy E, Cape Coral, FL
Fully refundable
The price is €93 per night from 13 Jul to 14 Jul
€93
per night
13 Jul - 14 Jul
9/10 Wonderful! (1,003 reviews)
"The property is updated and clean. Very close to nice restaurants with entertainment. Staff was friendly and helpful."
Reviewed on 10 Jul 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.